HORDB

ID: hor006824
Uniprot ID: O00253??84-132)
Protein name: Agouti-related protein
Gene name: Reg3a; Pap2;
Organism: Homo sapiens
Family: NA
Source: Human
Expression: Expressed primarily in the adrenal gland; subthalamic nucleus; and hypothalamus; with a lower level of expression occurring in testis; lung; and kidney.
Disease: NA
Comments: NA
Taxonomy: Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata (jawed vertebrates); Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea (apes); Hominidae (great apes); Homininae; Homo; Homo sapiens (Human)
GO MF: NA
GO BP: GO:0005102 signaling receptor binding; GO:0005184 neuropeptide hormone activity; GO:0070996 type 1 melanocortin receptor binding
GO CC: GO:0008343 adult feeding behavior; GO:0007218 neuropeptide signaling pathway; GO:0007623 circadian rhythm; GO:0060259 regulation of feeding behavior; GO:0032868 response to insulin; GO:0048571 long-day photoperiodism; GO:2000253 positive regulation of feeding behavior; GO:0009755 hormone-mediated signaling pathway; GO:0060135 maternal process involved in female pregnancy; GO:0007631 feeding behavior; GO:0042755 eating behavior

Sequence: SRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT
Length: 49
Propeptide: MLTAAVLSCALLLALPATRGAQMGLAPMEGIRRPDQALLPELPGLGLRAPLKKTTAEQAEEDLLQEAQALAEVLDLQDREPRSSRRCVRLHESCLGQQVPCCDPCATCYCRFFNAFCYCRKLGTAMNPCSRT
Signal peptide: MLTAAVLSCALLLALPATRG
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

Mass:		Formula:
Absent amino acids:		Common amino acids:
pI:		Basic residues:
Polar residues:		Hydrophobic residues:
Hydrophobicity:		Boman Index:
Half-Life:		Half-Life Yeast:
Half-Life E.Coli:		Aliphatic Index
Instability Index:		Extinction Coefficient cystines:
Absorbance 280nm: